In the early days of my TF ownership, I used to suffer from a loud clunking rattle from the driver's door.  When I remove the liner and rain excluding plastic, I found that the rear guide had either fallen off or was never installed.  It was lying in the bottom of the door (see first photo below.)  The part, after cleaning is in pic 2 and the blue plastic sheath which fits between the guide and the glass is in the last picture, mounted in the correct place before I replaced the cast guide block.  I was surprised by how heavy that cast lump of (Mazak??) guide block was.  I still have minor rattles from the door, but nothing like as bad as before replacing the heavy guide block.